Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae
نویسندگان
چکیده
منابع مشابه
Muscularis mucosae - the forgotten sibling.
Lamina muscularis mucosae sitting beneath mucosal surface of the digestive tract has received little attention to date compared with external smooth muscle layers. Motor activity of the muscularis mucosae shows a great regional and species difference. Autonomic innervation profile is also different from esophagus to colon or between animal species. Intracellular transduction mechanisms for moto...
متن کاملAntigenic Profile of Muscularis Mucosae and Muscularis Propria of the Urinary Bladder
Background: Differentiation between the muscularis mucosae (MM) and muscularispropria (MP) of the bladder remains challenging. Objective: To identify MM- and MP-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. Method: The expression of 12 protein antigens in 11 human bladder specimens was examined. There were 5 post radical cystectomy specim...
متن کاملComparison of motor reactivity of the colonic muscularis mucosae isolated from human, guinea pig and rat in vitro.
We have compared the reactivity to spasmogens of longitudinal muscularis mucosae isolated from the human, guinea pig and rat colon in vitro. The muscularis mucosae isolated from the human distal colon responded with a sustained contractions to carbachol (10 nM-30 microM), in a concentration-dependent manner, and the maximum contraction was comparable to that with high potassium concentration (1...
متن کاملUnique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder.
The muscularis mucosae, a type of smooth muscle located between the urothelium and the urinary bladder detrusor, has been described, although its properties and role in bladder function have not been characterized. Here, using mucosal tissue strips isolated from guinea pig urinary bladders, we identified spontaneous phasic contractions (SPCs) that appear to originate in the muscularis mucosae. ...
متن کاملPhenotypic change of muscularis mucosae in early invasive colorectal adenocarcinoma.
BACKGROUND Invasive colorectal adenocarcinomas have bundles of eosinophilic spindle cells, which are regarded as myofibroblasts, in their desmoplastic stroma, some of which are continuous with the muscularis mucosa. AIM To investigate the relation between the eosinophilic spindle cells and the muscularis mucosa based on their cytoskeletal phenotypes in early invasive colorectal adenocarcinoma...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1996
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1996.tb15170.x